Transcription Factors
Every cell relies on precise gene regulation to function properly. Transcription factors are essential proteins that control gene expression by binding to specific DNA sequences, playing a crucial role in...
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Cryo-EM Collaborations
Since 2019, our group has been actively supporting the operations of the Cryo-EM Facility hosted at NoLimits, University of Milan. Through the provision of both scientific and technical expertise, we collaborate with academic and private research groups across Italy and internationally. Our contributions span a diverse range of research areas, including small macromolecular complexes, viruses, amyloid fibrils, extracellular vesicles, and membrane proteins.
Some of our our most significant collaborations are:
Amyloid Fibrils
Proteins are essential molecular machines that must fold into precise three-dimensional structures to function properly. However, under certain conditions, some proteins missfold and aggregate into amyloid fibrils—highly ordered, insoluble structures...
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Riboregulated Enzymes
Enzymes are fundamental to life, catalyzing biochemical reactions with remarkable specificity and efficiency. However, their activity is not only regulated by traditional protein-based mechanisms but also by RNA molecules, leading...
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